Our collaborators from Alfredo Castello Lab , just published this nice story in Molecular Cell: System-wide Profiling of RNA-Binding Proteins Uncovers Key Regulators of Virus Infection Great work!! And happy of our small contribution.
Honoured to have contributed to the Budding topics series from Yeast. A review series for young PIs to discuss emerging concepts and topics. From transcriptional complexity to cellular phenotypes: lessons from yeast. Pelechano V. Yeast. 2017 Sep 3. doi:10.1002/yea.3277
Our collaborators from Sebastian Chavez lab (Seville) have just published a new paper showing the crosstalk between ribosome biogenesis and transcription elongation. Glad to have contributed to this story. The ribosome assembly gene network is controlled by the feedback regulation of transcription elongation. Fernando Gómez-Herreros Thanasis Margaritis Olga Rodríguez-Galán Vicent Pelechano Victoria Begley Gonzalo Millán-Zambrano Macarena Read more about crosstalk between ribosome biogenesis and transcription elongation[…]
We have just published our first work 100% performed in our new lab at SciLifeLab-Karolinska Institutet. It has been a great collaboration with Dr. Paula Alepuz from the University of Valencia (Spain) eIF5A facilitates translation termination globally and promotes the elongation of many non polyproline-specific tripeptide sequences. Pelechano V# and Alepuz P#. Nucleic Acids Res. 2017 May 26. doi: Read more about Using 5PSeq to unravel eIF5A dependent ribosome stalling[…]
Amazing work from our collaborators from Boone, Andrews and Myers Lab. A landmark in genetics that for sure will pave the way for many future discoveries. M. Costanzo*, B. VanderSluis*, E. N. Koch*, A. Baryshnikova*, C. Pons*, G. Tan, et al. A global genetic interaction network maps a wiring diagram of cellular function. Science, 2016; Read more about A global genetic interaction network[…]
We want to congratulate our collaborators from Sandelin and Jensen Lab for leading this great paper in Nature Genetics. This is a great example of how to combine different genome-wide methodologies to improve our understanding of the transcriptome organization. Proud of our contribution to this work. Principles for RNA metabolism and alternative transcription initiation within Read more about Principes of eukaryotic RNA metabolism[…]