pelechanolab – Vicent Pelechano Laboratory

TEAM

Vicent Pelechano, PhD

Associate Professor.

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Vicent studied Biochemistry at the University of Valencia (Spain) where he also obtained a PhD. He joined EMBL (Germany) in 2009 as a postdoctoral fellow and became Staff Scientist. He is group leaderat KI (MTC) since 2016 and SciLifeLab and Wallenberg Academy Fellow.

Yerma Pareja

PhD student

Yerma obtained a Master degree and Bachelor in Biomedicine by the University of Seville (Spain). She joined our lab on Sep 2017.

Yujie Zhang

PhD student

Yujie obtained a Bachelor and a Master degree in Viticulture and Enology at the Northwest A&F University (Shaanxi). She joined our lab in Oct 2017.

Susanne Huch, PhD

Researc Specialist

Susanne worked as research specialist at the Universities of Heidelberg, Arizona and Umeå. She obtained her PhD in at Umeå University. She joined our team in 2017.

Lilit Nersisyan, PhD

PostDoc

Lilit studied Biotechnology and computer Sciences in Yerevan (Armenia). She obtained her Phd in 2017 (Leipzig Germany & Yerevan Armenia). She joined our lab in 2018.

Donal Barrett

PhD student and Resear Technician

Donal studied Sport Sciences and Nutrition at the University of Limerick (Ireland) and Stockholm. He specialized on Molecular Biology at Umeå University, Stockholm University and Karolinska Institutet. He joined our team on 2018 as Reseach Technician and in 2022 as PhD student.

Eva Brinkman, PhD

PostDoc

Eva studied at the Technical University Delft and Leiden University. She did her Phd in 2019 (Netherlands Cancer Institute). She joined our lab in 2019.

Ryan Hull, PhD

PostDoc

Ryan studied at the University of Birmingham. He did his Phd in 2018 (Babraham Institute, University of Cambridge). He joined our lab in 2019.

Irene Stevens

PhD student

Irene obtained a BA at Hunter College (NY, USA) and a MD at Oradea (Romania). She worked as junior bioinformatician at NIH, Cornell and Karolinska. She joined our lab in July 2020.

Guido Baselli, PhD

PostDoc

Guido studied at the University of Milan and obtained a Phd in Clinical and Experimental Medicine in 2020. He joined our lab in 2021.

Marcel Tarbier, PhD

PostDoc

Marcel studied Biology at Dresden University of Technology and Bioinformatics and Systems Biology at Freiburg University. In 2021 he obtained his PhD in Molecular Bioscience (single-cell genomics) at Stockholm University, and joined our lab.

Mengjun Wu, PhD

PostDoc

Mengjun studied Pharmacy at Sichuan University and CAS. She then studied Life Science Informatics at the University of Bonn (Germany). In 2021 she obtained her PhD in computational and RNA biology at the University of Copenhagen, and a bridging postdoc in Spain. She joined our lab in at the end of 2021.

Honglian Liu

Research Assistant

Honglian obtained a Bachelor degree at the China Agricultural University in Beijing, and a Master in Molecular Biology from the University of Gothenburg.She Joined our lab in 2022.

Paulius Baltrusis, PhD

Research Technician

Adriana Carvajal Jimenez

Research Technician

Carlos Santolaria

PostDoc

——————– Affiliated ——————–

Eduardo Sagredo, PhD

PostDoc – SU

Eduardo studied at La Frontera University, Temuco. He did his Phd in 2018 (University of Chile). He is affiliated to the Visa (SU) lab and collaborates with us as part of the SciLifeLab-SU program.

Mandy Meijer, PhD

PostDoc – MDC Berlin

Weronika Danecka

PhD student – University of Edinburgh

Weronika Danecka is a PhD student on the MRC Precision medicine DTP. Main supervisor: Dr. Edward Wallace. https://ewallace.github.io

Funding

We thank the suport that makes possible our research.

Latest news

Postdoc in Computational RNA biology and Metagenomics

We have an open position focussed on the development of novel computational approaches to study gene expression and RNA metabolism in complex bacterial samples. The candidate will focus on the multiomic integration of a wide variety of genomic data (metagenomics, metatranscriptomics, metadegradomics and phenotypic data). This will include the study of the crosstalk between translation regulation and mRNA decay in response to environmental and drug perturbations using novel tools that our laboratory has recently developed (Huch, Nersisyan et al. Nat microbiology 2023).

Deadline 24.Jun.2023

Metadegradome paper published in Nat Microbiology

Extremely happy to see our work our on metadegradomics published in Nature microbiology.
Kudos to Susanne and Lilit who spearheaded this work.

Postdoctoral studies in single-cell RNA biology

We have an open postdoctoral position in single-cell RNA biology. The available postdoctoral position concerns developing and applying novel genomic approaches to study RNA-protein interaction and subcellular localization at single-cell level. The candidate will focus on investigating how translation and mRNA stability are regulated, and how the disruption of those processes across cells alter cellular phenotypes in health and disease.

Deadline 27 May 2023

Transcriptional memory story published in Nat Comms.

Very happy to see our or story showing how differential regulation of mRNA stability modulates transcriptional memory in budding yeast. A great work leaded by Bingnan Li in our lab.

Not1 and Not4 inversely determine mRNA solubility and co-translational events

Our collaboration with Martine Collart Lab is finally out in Genome Research. Here we used 5PSeq to study ribosome dynamics in insoluble fractions, that are not accessible to methods such as ribosome profiling. Great collaboration.

Postdoctoral position in single-cell RNA biology

Deadline 10 March 2023

Collaborative paper published in Nat Cancer

A great manuscript led by our collaborators from the Fendt Lab showing how targeting palmitate processing inhibits breast cancer-derived lung metastasis.

Postdoctoral position in RNA biology

We have an open postdoctoral position in RNA biology. The available postdoctoral position concerns developing and applying novel genomic approaches to study RNA-protein interaction. The candidate will focus on investigation the dynamic interaction between the transcriptome and the proteome, and how the disruption of those interaction can be used to modulate gene expression and cellular phenotypes in health and disease.

Deadline 30 January 2023

Research Technician in Clinical Genomics

We have one open position for a Research Technician in Clinical Genomics. Please find detailed information and link to the application system (MyNetwork) following the link below. Application deadline is September 24th 2022.

OPUSeq paper published

Happy to present our first incursion into Clinical Genomics. It will not be the last 🙂