We want to congratulate our collaborators from Sandelin and Jensen Lab for leading this great paper in Nature Genetics. This is a great example of how to combine different genome-wide methodologies to improve our understanding of the transcriptome organization. Proud of our contribution to this work. Principles for RNA metabolism and alternative transcription initiation within Read more about Principes of eukaryotic RNA metabolism[…]
Great collaboration with the Akhtar group. Nice to see this nice paper out. Functional interplay between MSL1 and CDK7 controls RNA polymerase II Ser5 phosphorylation. Chlamydas et al. Nature Structural & Molecular Biology. 2016 23, 580–589 doi:10.1038/nsmb.3233
We jut got published a new paper describing alternative methods for the genome-wide identification of 5’RNA ends. In this paper we do not only describe in detail our previous 5PSeq approach, but also new methods to identified alternative 5’RNA modifications. In particular we provide alternatives to use of the recently discontinued Tobacco Acid Pyrophosphatase. Genome-wide Read more about Protocol for genome-wide 5’RNA identification[…]